The San Francisco 49ers and Seattle Seahawks clash in a high-stakes battle for the NFC Championship Game this Saturday. San Francisco (12-5) is coming off a narrow 23-19 wild-card victory over Philadelphia. Meanwhile, Seattle (14-3) is fresh from a bye as the top seed in the NFC. Over the regular season, these two teams split their matchups. Seattle quarterback Sam Darnold is in question after sustaining an oblique injury during practice this week. The 49ers are also dealing with injuries, as receiver Ricky Pearsall is questionable, and tight end George Kittle is out for the season after a recent Achilles injury.
Kickoff at Seattle’s Lumen Field is set for 8 p.m. ET. In terms of betting, Seattle stands as 7-point favorites according to the latest odds from DraftKings, with an over/under of 44.5 points. Before making any picks, you should check out insights from the SportsLine Projection Model.
This model simulates every NFL game 10,000 times and has accrued over $7,000 in profit for $100 players on its top-rated NFL picks since its inception. As the divisional round kicks off, the model boasts a solid 53-37 record on top-rated picks that stretch back to 2024. Those who have followed its NFL betting recommendations could have seen lucrative returns.
Now, the model is set on the 49ers vs. Seahawks matchup. You can visit SportsLine for picks. Here are the odds and trends for the 49ers vs. Seahawks:
| 49ers vs. Seahawks | Seattle -7 at DraftKings Sportsbook |
| 49ers vs. Seahawks | 44.5 points |
| 49ers vs. Seahawks | Seattle -305, San Francisco +245 |
| 49ers vs. Seahawks | See picks at SportsLine |
| 49ers vs. Seahawks | Fubo (Try for free) |
Why Seattle is Positioned to Win
Veteran quarterback Sam Darnold leads the Seattle offense. In the 17 games this season, he has completed 67.7% of his passes, racking up 4,048 yards and throwing 25 touchdowns against 14 interceptions for a 99.1 rating. In a previous matchup against the 49ers, he threw for 198 yards completing 20 of 26 passes in a 13-3 victory on January 3. Additionally, in a thrilling overtime victory against the Los Angeles Rams, he completed 22 of 34 passes for 270 yards and two touchdowns.
His main target has been wide receiver Jaxon Smith-Njigba. Over 17 games, he recorded 119 catches for 1,793 yards and 10 touchdowns. Smith-Njigba has provided explosive plays with 27 receptions of 20-plus yards, accumulating 528 yards after the catch and achieving 79 first-down conversions. Against the 49ers this season, he has tallied 15 receptions for 208 yards.
Why San Francisco Can Compete
Quarterback Brock Purdy has stepped up, showcasing solid performances, including a standout game in the Wild Card victory against Philadelphia. He completed 18 of 31 passes for 262 yards, tossing two touchdowns but also throwing two interceptions. Over nine regular-season games, he accumulated a completion rate of 69.4%, amassing 2,167 yards with 20 touchdown passes against 10 interceptions.
Christina McCaffrey has been a dual threat for San Francisco, serving as both their leading rusher and receiver. In the regular season, he ran for 1,202 yards on 311 carries, scoring 10 rushing touchdowns. He also caught 102 passes for 924 yards and seven receiving touchdowns. In the Wild Card round, he had an impressive day with 15 carries for 48 yards, along with six receptions for 66 yards and two touchdowns.
How to Approach Your Betting
SportsLine’s analysis leans towards the total points going Over, projecting 48 combined points. Additionally, their simulations suggest one side of the spread consistently hits more than 50% of the time. Get detailed insights on the pick at SportsLine.
Curiosity surrounds which team will take the victory in the Seahawks vs. 49ers face-off and which side of the spread is statistically favored. For expert picks and model analysis that has yielded over $7,000 in profit, click here to explore your betting options.
